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Gabriel tests for root cause of B12 deficiency: pernicious anemia (intrinsic factor antibodies, parietal cell antibodies), gut malabsorption, dietary insufficiency, medication-induced.
Gabriel tests for root cause of B12 deficiency: pernicious anemia (intrinsic factor antibodies, parietal cell antibodies), gut malabsorption, dietary insufficiency, medication-induced. He uses methylcobalamin (active form) or hydroxocobalamin, bypasses absorption issues with sublingual, nasal spray, or injections, addresses gut health and stomach acid, treats H. pylori if present, and monitors methylmalonic acid and homocysteine (functional markers) not just serum B12. Recognizes B12 deficiency can cause permanent neurological damage if untreated, so aggressive repletion critical.
Standard Treatment
Oral B12 supplementation (often cyanocobalamin - synthetic form), B12 injections (usually monthly, but often insufficient frequency initially), treat underlying cause if identified, folic acid supplementation.
The Problem
Uses cyanocobalamin instead of methylcobalamin (active form), monthly injections often insufficient for severe deficiency or neurological symptoms (need weekly or more initially), doesn't test MMA or homocysteine (functional markers better than serum B12), misses pernicious anemia diagnosis (doesn't test antibodies), doesn't optimize stomach acid or treat gut issues, doesn't recognize 'normal' B12 (>200) is often insufficient (optimal >600-800), neurological damage can be permanent if not caught early.
A comprehensive, tiered approach combining supplements, herbs, and advanced therapies
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What's Included
Available through Fullscript
Practitioner-Grade — Not Available on Amazon
What's Included
Whole food supplements by Standard Process
What's Included
Standard Process + Matter peptides
For non-vegetarians: increase B12-rich foods (grass-fed red meat, liver and organ meats, wild-caught fish, shellfish, eggs, dairy if tolerated), however dietary changes alone often insufficient if absorption issue present. For vegetarians/vegans: supplementation mandatory (cannot get adequate B12 from plant foods despite nutritional yeast containing some), consider eating shellfish or eggs if willing for highly bioavailable B12, inadequate stomach acid: avoid antacids, consider digestive bitters before meals, apple cider vinegar.
If pernicious anemia: lifelong supplementation required (can't absorb oral B12 well, need sublingual, nasal, or injections), stop PPIs and H2 blockers if possible (work with doctor on alternatives for reflux), treat underlying gut issues, alcohol reduction or elimination (depletes B12 and damages gut), regular monitoring of B12 status, watch for neurological symptoms (tingling, numbness, balance issues, cognitive decline) and treat aggressively, if metformin user: supplement B12 (metformin depletes B12).
Mind, Body & Spirit
True healing requires addressing all dimensions of health. These evidence-based practices complement physical treatment protocols.
Support for memory and cognitive issues from B12 deficiency.
Supporting neuroplasticity and recovery from neurological damage.
Physical therapy for neurological symptoms (ataxia, neuropathy).
Pacing activities during recovery from severe deficiency.
Connect with practitioners who specialize in treating B12 Deficiency / Pernicious Anemia naturally using root-cause approaches. Our directory features qualified professionals trained in functional medicine, integrative health, and holistic protocols.
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Curated for B12 Deficiency / Pernicious Anemia
Supplements + Chinese herbal medicine via Fullscript
Standard Process + classical TCM formulas
Standard Process + advanced peptide therapy
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