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Actaea racemosa
Tradition of Use: Western, Native American
Serotonergic activity, possible estrogen receptor modulation, anti-inflammatory
Tincture, capsule
20-40mg extract 2x daily (standardized to triterpene glycosides)
Triterpene glycosides, cimicifugoside, isoferulic acid
May interact with hepatotoxic drugs; theoretically with hormone therapy
Liver disease; pregnancy; hormone-sensitive cancers (debated)
Evidence Level:
Good - effective for menopause symptoms
Clinical Notes:
Mechanism unclear (not directly estrogenic); monitor liver function; takes 4-8 weeks
Sheng Ma
Reduces hot flashes and night sweats during menopause
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
Hypericum perforatum
Inhibits serotonin, dopamine, norepinephrine reuptake; modulates GABA and glutamate receptors
Silybum marianum
Hepatoprotective via silymarin (antioxidant, anti-inflammatory, regenerates hepatocytes)
Zingiber officinale
Anti-inflammatory, antiemetic, warming circulatory stimulant, digestive, analgesic