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Hericium erinaceus
Tradition of Use: TCM, Japanese traditional, Western
Nerve growth factor (NGF) stimulation, neuroprotective, promotes myelin, cognitive enhancement
Capsule, powder, extract, cooked mushroom
500-3000mg extract daily or 20-50g fresh mushroom
Hericenones, erinacines, polysaccharides, beta-glucans
May interact with diabetes medications, anticoagulants (theoretical)
None significant; rare allergic reactions
Evidence Level:
Good - promising neurological effects
Clinical Notes:
Stimulates NGF synthesis; neuroprotective; improves cognition; safe; edible and medicinal
Lion's mane supports nerve growth factor
BUT: requires consistent use for 2-3 months to see cognitive benefits
Lion's mane may prevent cognitive decline
BUT: human studies are limited
Lion's mane is a culinary mushroom
BUT: supplement extracts are more concentrated
Lion's mane supports gut health
BUT: rare allergic reactions occur
This information is for educational purposes. Always consult with a qualified healthcare provider before starting any herbal protocol or supplement regimen.
Trametes versicolor
Potent immunomodulation via PSK/PSP, anticancer adjunct, antiviral
Ganoderma lucidum
Immunomodulation via polysaccharides, beta-glucans, anti-inflammatory via triterpenes
Grifola frondosa
Immunomodulation via D-fraction, blood sugar regulation, anticancer adjunct