HMB (Beta-Hydroxy Beta-Methylbutyrate)

Mechanism of Action

Leucine metabolite; reduces muscle breakdown, enhances muscle protein synthesis, supports recovery

Primary Applications

Muscle wasting

Sarcopenia

Athletic performance

Post-surgery recovery

Aging

Recommended Dosage

3g/day (divided doses)

Available Forms

HMB calcium, HMB free acid

Top Brands

NOWJarrowBulk SupplementsOptimum Nutrition

Synergies

Works synergistically with:

Creatine

BCAAs

Vitamin D

Protein

Natural Food Sources

Alfalfa; Grapefruit; Catfish (trace amounts)

Interactions

May lower cholesterol

Contraindications

None at therapeutic doses

Clinical Notes

Leucine metabolite; anti-catabolic; benefits elderly and athletes; free acid form faster absorption; modest effects vs other ergogenics

Quick Overview

CategoryAmino Acids

GBS Score70/100

IDAA015

Key Points

Evidence-based dosing

Mechanism documented

Interaction screening

Synergy optimization

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This information is for educational purposes. Always consult with a qualified healthcare provider before starting any new supplement protocol.

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