ModerateGBS: 77 (Moderate-High Risk)nutrition

Neuropathy Recovery Protocol

Developer: Various integrative neurologists

3-12 months, nerve regeneration is slow (1mm/day)

Protocol Overview

Protocol to address root causes and support nerve healing using targeted nutrients, alpha-lipoic acid, and lifestyle modification. Diabetic neuropathy most studied.

Conditions Treated

Peripheral neuropathy

diabetic neuropathy

chemotherapy-induced neuropathy

Protocol Steps

Address root cause: Diabetes (tight blood sugar control - A1C <7%, ideally <6.5%), B12 deficiency (often metformin-induced - supplement), toxic exposure (alcohol, chemo, heavy metals - address), hypothyroidism (treat), autoimmune (evaluate)

Blood sugar control: If diabetic, this is #1 - CGM (continuous glucose monitor) to optimize, low-carb or ketogenic diet, exercise, metformin/SGLT2 inhibitors

Alpha-lipoic acid (ALA): 600-1200mg daily (most studied for diabetic neuropathy - improves symptoms, nerve conduction, multiple RCTs) - take on empty stomach for best absorption

Vitamin B12: High-dose methylcobalamin 1000-5000mcg sublingual daily OR weekly IM injections (myelin synthesis, nerve healing) - test first, many neuropathy patients deficient

Methylated B-complex: B1 (benfotiamine 300-600mg - fat-soluble B1 for diabetic neuropathy), B6 50mg (P5P form - but limit to 50mg, high B6 can cause neuropathy), folate, B2

Acetyl-L-carnitine: 1500-3000mg daily (mitochondrial support, nerve regeneration) - studied in diabetic and chemo-induced neuropathy

Vitamin D: Optimize 50-80 ng/ml (deficiency associated with neuropathy)

Omega-3: 2-3g EPA/DHA (anti-inflammatory, nerve membrane)

Vitamin E: 400-800 IU mixed tocopherols (antioxidant, studied in diabetic neuropathy)

Magnesium: 400-800mg (nerve function, often deficient)

Curcumin: 1-2g daily (anti-inflammatory, neuroprotective)

Evening primrose oil: 2-4g (GLA for nerve inflammation)

CBD oil: 25-50mg 2x/day (pain management, neuroprotection)

Topical: Capsaicin cream 0.075% (depletes substance P, pain relief) or compounded ketamine/gabapentin cream

Physical therapy: Desensitization, balance training, gait training

TENS unit: Transcutaneous electrical nerve stimulation for pain

Red light therapy: 670-850nm NIR for nerve healing, mitochondrial support

Avoid: Neurotoxins (alcohol, tobacco), tight shoes/socks (circulation), extreme temperatures, medications causing neuropathy (check current meds)

Acupuncture: Some benefit for pain management

Hyperbaric oxygen: Emerging evidence for nerve healing (1.5 ATA)

Key Resources

Alpha-lipoic acid meta-analyses, "Numb Toes and Aching Soles" by John Senneff, neuropathy research literature

Contraindications & Risks

ALA can lower blood sugar (monitor if diabetic), high-dose B6 >200mg can cause neuropathy (ironic - limit to 50mg)

Important Notes

Peripheral neuropathy affects 30+ million Americans. Causes: Diabetes (most common), B12 deficiency (especially metformin use), chemotherapy (platinum agents, taxanes), alcohol, hypothyroidism, autoimmune. Symptoms: Numbness, tingling, burning pain, typically feet/hands (stocking-glove distribution). Nerve damage hard to reverse but can stop progression and improve symptoms. Alpha-lipoic acid has strongest evidence - multiple RCTs in diabetic neuropathy showing symptom improvement. Dosing 600mg+ daily. Antioxidant and improves nerve blood flow. B12 crucial - methylcobalamin form better for nerve healing, many neuropathy patients deficient (especially on metformin). Benfotiamine (fat-soluble B1) specific for diabetic complications. Acetyl-L-carnitine helps mitochondria in nerves. Blood sugar control is foundation in diabetic neuropathy - every 1% A1C reduction reduces neuropathy risk 40%. Tight control can reverse early neuropathy. Pain management challenging - gabapentin, pregabalin, duloxetine are conventional options, CBD oil emerging alternative. Nerve regeneration is slow (1mm/day axon growth) - takes months. Combination approach best.

Also Effective For

Peripheral Neuropathy

Key Supplements & Herbs in This Protocol

Supplements

L-Carnitine

Critical Safety Warning

This protocol is documented for educational purposes only. The Gabriel Bullshit Score (GBS) of 77 reflects significant institutional response and controversy. Some alternative health protocols have resulted in serious harm or death.

Always consult with qualified healthcare professionals before beginning any treatment. Do not delay or forego proven medical care.

Quick Overview

Evidence LevelModerate

GBS Score77 / 100

Categorynutrition

DeveloperVarious integrative neurologists

Duration3-12 months, nerve regeneration is slow (1mm/day)

About GBS Score

The Gabriel Bullshit Score reflects the magnitude of institutional response, controversy, and documented concerns. Higher scores indicate greater institutional pushback, not necessarily inefficacy. This is a research tool, not medical advice.